Table 1. Pharmacokinetics of non-glycosylated and glycosylated rhGM-CSF in mice after a single ip injection.

C_max
(nmol/mL)

t_max
(min)

t_1/2 α
(min)

t_1/2 β
(min)

CL
(mL/min)

non-glycosylated rhGM-CSF

0.018 ± 0.001

20

10 ± 2

260 ± 80

0.26 ± 0.07

glycosylated rhGM-CSF

0.0028 ± 0.0005

30

60 ± 10

1,500 ± 200

0.09 ± 0.02